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Yongcheng Zhou

Curriculum Vitae

Department of Mathematics

Center for Theoretical Biological Physics
University of California San Diego
9500 Gilmann Drive, DEPT 0112
La Jolla, CA 92093

 

tel: (517) 898-5113
fax: (858) 534-4974

e-mail: yozhou@math.ucsd.edu

Education |  Experience | Research interests |  Publications  | Presentations 

 Honors and awards | Memberships | Computer skills  | References 

 

EDUCATION
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Ph.D. Applied Mathematics, Michigan State University, 2006
PhD Thesis: Matched Interface and Boundary Method and Its Applications to Implicit Solvent Modeling of Biomolecules
Advisor: Professor Guowei Wei
M.E., Mechanical Engineering
Minor: Computational Fluid Dynamics
1999, China Academy of Launch Vehicle Technology, Beijing, China
B.E.,  Mechanical Engineering
Minor: Fluid Dynamics
1996, Northwestern Polytechnical University, Xi'an, China
EXPERIENCE
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Postdoctoral Research Fellow
2006 - Present
Department of Mathematics and Center for Theoretical Biological Physics
University of California San Diego
Mentors: Professor Michael J. Holst, Professor J. Andrew McCammon
Teaching Assistant
Fall 2002, Spring and Fall 2003, Spring and Fall 2004, Fall 2005, Spring and Summer 2006
Department of Mathematics, Michigan State University
Research Assistant
Summer 2003, Summer 2004, Spring and Summer 2005
Department of Mathematics, Michigan State University
Research Assistant
2000 - 2002
Department of Computational Science, National University of Singapore
RESEARCH INTERESTS
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  • Applied analysis, numerical analysis and scientific computing;
  • Mathematical modeling and computational simulation for biological problems: Continuum modeling of molecular electrostatics; Electrostatic mediated molecular diffusion and its applications to molecular transportation, reaction and cell signaling; Continuum modeling of macromolecular conformational change;
  • Computational fluid dynaimics; Biofluid modeling and simulation.
PUBLICATIONS
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  1. Recent progress in numerical methods for the Poisson-Boltzmann equation in biophysical applications,  B. Lu, Y. C. Zhou, M. Holst and J. Andrew McCammon, Communications in Computational Physics, In press.
  2. Continuum Simulations of Acetylcholine Consumption by Acetylcholinesterase: A Poisson-Nernst-Planck Approach, Y. C. Zhou, B. Lu, G. Huber, M. Holst and J. Andrew McCammon, Journal of Physical Chemistry B, (112), 270-275, 2008.
  3. Nonlinear elastic modeling of macromolecular conformational change induced by electrostatic forces, Y. C. Zhou, M. Holst and J. Andrew McCammon, Journal of Mathematical Analysis and Applications, (340) 135-164, 2008.
  4. Electrodiffusion: A continuum-modeling framework for biomolecular systems with realistic spatiotemporal resolution , B. Lu, Y. C. Zhou,  G. A. Huber, S. D. Bond, M. Holst and J. Andrew McCammon, Journal of Chemical Physics, (127), 135102, 2007.
  5. Multiresolution molecular surfaces, G. W. Wei, Yuhui Sun, Y. C. Zhou and Michael Feig, arXiV: math-phy/0511001, Preprint.
  6. Highly accurate biomolecular electrostatics in continuum dielectric environments, Y. C. Zhou, Michael Feig and G. W. Wei, Journal of Computational Chemistry, (29), 87-97, 2008.
  7. Matched interface and boundary (MIB) method for elliptic problems with sharp-edged interfaces, Sining Yu, Y. C. Zhou and G. W. Wei, Journal of Computational Physics,(224),729-756, 2007.
  8. On the fictitious-domain and interpolation formulations of the matched interface and boundary (MIB) method, Y. C. Zhou and G. W. Wei, Journal of Computational Physics, (219), 228-246, 2006.
  9. High order matched interface and boundary (MIB) method for elliptic equations with discontinuous coefficients and singular sources, Y. C. Zhou, Shan Zhao, Michael Feig and G. W. Wei, Journal of Computational Physics, (213), 1-30, 2006.
  10. A practical spectral method for hyperbolic conservation laws, Yuhui Sun, Y. C. Zhou and G. W. Wei, Journal of Computational Physics, (214), 228-246, 2006.
  11. High resolution conjugate filters for the simulation of flows, Y. C. Zhou and G. W. Wei, Journal of Computational Physics, (189), 150-179, 2003.
  12. DSC solution for flow in a staggered double lid driven cavity, Y. C. Zhou, B. S. V. Patnaik, D. C. Wan and G. W. Wei, International Journal for Numerical Methods in Engineering, (57), 211-234, 2003.
  13. Controlling flow turbulence, S. Guan, Y. C. Zhou, G. W. Wei, and C.-H. Lai, Chaos, (13), 64-70, 2003
  14. Conjugate filters with spectral-like resolution for 2D incompressible flow, Yun Gu, Y. C. Zhou and G. W. Wei, Computers & Fluids, (33), 777-794, 2003.
  15. Shock-capturing with natural high frequency oscillations, Y. C. Zhou, Yun Gu and G. W. Wei, International Journal for Numerical Methods in Fluids, (41), 1319-1338, 2003.
  16. Numerical solution of incompressible flows by discrete singular convolution, D. C. Wan, Y. C. Zhou and G. W. Wei, International Journal for Numerical Methods in Fluids, (38), 789-810, 2002.
  17. Comparison of the discrete singular convolution algorithm and the Fourier pseudospectral method for solving partial difference equations, S. Y. Yang, Y. C. Zhou and G. W. Wei, Computer Physics Communications, (143), 113-135, 2002.
CONFERENCES/PRESENTATIONS
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  • SIAM Conference on Mathematics for Industry: Challenges and Frontiers Philadelphia, 10/09-10/11, 2007
  • Applications of Analysis to Mathematical Biology Conference Duke University, 05/21-05/23, 2007
  • Midwest Quantitative Biology Conference Michigan State University, 09/29-10/01, 2006
  • Mathematics/Biophysics Seminar University of Michigan, 06/07, 2006
  • Biocomplexity Workshop: Applications of Methods of Stochastic Systems and Statistical Physics in Biology University of Notre Dame, 10/28-10/30, 2005
  • Midwest Numerical Analysis Conference University of Iowa, 05/20-05/22, 2005
  • Midwest Computational Structural Biology Workshop Michigan State University, 04/30-05/01, 2005
  • IMA Summer Program: Probability and Partial Differential Equations in Modern Applied Mathematics University of Minnesota, 07/21-08/01, 2003

HONORS AND AWARDS
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  • Paul and Wilma Dressel Endowed Scholarship, Michigan State University, 2005.
  • Research Award on Quantitative Biology and Modeling Initiative, Michigan State University, 2004-2005.

MEMBERSHIPS
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  • American Mathematical Society (since 2002)
  • Society for Industrial and Applied Mathematics (since 2002)
  • Biophysical Society (since 2006)

COMPUTER SKILLS
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Languages
Fortran, C, C++, Perl, Python, Java
Mathematical Software
Matlab, Mathematica, Maple
Computational Chemistry Software
CHARMM, Delphi, APBS, VMD
Statistical Software
SAS
Typesetting Software
LaTeX
Operating Systems
Unix, LINUX, Windows

REFERENCES
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Available upon request.